Per an October 2014 interview with TVline, celebrating the 200th episode of the show, Jared Padalecki states 'Death's Door' is his favorite episode of the series thus far. Jensen Ackles revealed that it's also his favorite episode as well. Bobby is pushed into the trauma OR and a Dr. orders 80 grams of mannitol.
12 Funniest Supernatural Episodes to Watch or Rewatch
#1 The French Mistake Season 6, Episode 15.
#2 Mystery Spot Season 3, Episode 11.
#3 Changing Channels Season 5, Episode 8.
#4 Fan Fiction Season 10, Episode 5.
#5 Ghostfacers Season 3, Episode 13.
#6 The Real Ghostbusters Season 5, Episode 6.