You'll want to make sure that the sports betting sites that you play on are legal and regulated in your state. All of our recommended sites fit the bill, and we provide full details on state availability for each.
If you're new to the betting world, you can start with the moneyline. It's an easier bet to research and you can pick the favorite if you want to. Moneyline bets are less risky and simpler because if the team you bet on wins, you win your bet.