In order to place wagers on bet365, you must be at least 21 years or older. You also must be located within a state where bet365 is allowed (currently New Jersey, Colorado, Ohio, Iowa, Louisiana, or Virginia), although you can sign up for an account and even deposit or withdraw funds from elsewhere.
For online sports betting, patrons must be physically located within the state or jurisdiction to place bets on the state-sanctioned platform(s). Customers don't need to be a resident of the state where they want to place a bet. Many regulated sports betting sites operate in numerous markets.