What does +2 European Handicap Mean? The handicap with the positive coefficient is the underdog team. A bet on European handicap +2 for Cagliari means: If the team wins, draws or loses by 1, your bet wins. If the team loses by 2 or more, your bet loses.
When betting on a handicap market on soccer, the team supposedly less likely to win, given the odds, is awarded a goal or the favourite  is given handicap points before the match even starts as far as the bet is concerned. So, the favourite will start with a handicap of -1, -2, -3, etc.